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MultIwavelength LAser for fast DiagnOstic in biomedical and manufacturing applications

MILADO

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Published on 4 December 2024

MILADO​: MultIwavelength LAser for fast DiagnOstic in biomedical and manufacturing applications


MILADO is dedicated to creating a groundbreaking platform for the cost-effective and large-scale production of mid-infrared (MIR) lasers. At the heart of MILADO is the innovative technology upscale of Quantum Cascade Laser (QCL) epitaxy on large-area substrates and the pioneering development of direct III-V epitaxy on silicon. By integrating QCL and Si-based MIR photonics using Complementary Metal Oxide Semiconductor(CMOS)-based technology, MILADO merges III-V and silicon photonics technologies. This versatile platform will revolutionize markets by enabling new sensors for personal medical diagnostics and edge-sensors in chemical production​




 

Starting date: 01/06/2024   
Lifetime
: 36 months


 

​Program in support

HORIZON-CL4-2023-DIGITAL-EMERGING-01-53 ​


 

Status of project : starting


CEA-Leti's contact

                                               

 

Project Coordinator

  • ​​TECHNIKON​
  • CEA-Leti: Scientific coordinator
  • IAF​: Technical coordinator


Partners 



Costs: 4,943,399.27 €​​

Funding: 100% EU-funded​​

 

Number of patentsn/a


More info on website

Stakes
  • Develop large scale III-V epitaxy for low-cost manufacturing of QCLs.
  • Enable economical, high-volume fabrication of a universal MIR photonic integrated platform.
  • Prototype novel sensors for personal medical diagnostics or edge-sensors in chemical production opening new markets.
  • Demonstrate process control and medical diagnostics from MIR chemical imaging histopathology to non-invasive continuous glucose monitoring.
  • Accelerate the analysis time in infrared spectral histopathology by 100 times.

OBJECTIVES

MILADO will provide a robust and universal technology platform for low-cost and large volume fabrication of mid infrared (MIR) lasers enabling novel sensors in medicine and production. Key innovation is the technology upscale of the epitaxy of Quantum-Cascade- Lasers (QCLs) on large area substrates and the development of concepts for direct III-V-epitaxy on silicon.

​Merging III-V and Si-photonics by integrating QCLs and Si-based MIR photonics using CMOS-based technology well-established should reduce the cost production. Indeed but very costly III/V-technology-based manufacturing of QCL light sources for spectroscopic applications will be replaced by a cost effective and scalable manufacturing technology on CEA’s CMOS Pilot Line bringing MIR technology out of its niche

Another building block of MILADO towards a general platform that can be extended for further integration of sensors and actuators in MEMS technology are MIR-PICs made from Ge/SiGe-structures for the definition of waveguides, combiners and any other passive devices required to handle the optical connection of QCLs.

MILADO’s technology will open up new markets by enabling novel sensors for personal medical diagnostics or edge-sensors in chemical production. The versatility of the approach will be demonstrated in use cases covering process control and medical diagnostics reaching from the hospital to the patient covering waste anaesthetic gas detection, histopathology to biomarker monitoring. ​


IMPACT

The MILADO project envisions revolutionizing the field of mid-infrared optical sensing by developing compact, economical light sources that unlock the powerful MIR region. By leveraging large-scale III-V epitaxy and cost-effective CMOS/MEMS fabrication, MILADO seeks to democratize access to advanced MIR sensor technology.

This transformation will enable innovative applications across various sectors, including biomedical diagnostics, industrial process control, and environmental monitoring. MILADO’s ultimate goal is to make high-performance MIR sensor solutions more accessible, affordable, and versatile, paving the way for new markets and widespread adoption.​